Kratom for Depression and Anxiety: Types, Dosage and Side Effects

Kratom for Depression

Things to consider

Kratom is a tropical tree native to South Asia. Kratom leaves or an extract from its leaves have been used in alternative medicine for chronic pain and other conditions. Many people also use kratom to treat symptoms of depression or anxiety on their own. While some evidence suggests that certain strains of kratom may help relieve these symptoms, more research is needed. The United States Food and Drug Administration (FDA) has not approved kratom for the treatment of depression or anxiety. Kratom is considered a dietary supplement, so it is not regulated by the FDA. There are also others who use mushrooms and kratom together. This helps in decreasing anxiety as well as depression. If you are thinking about using kratom to treat symptoms of depression or anxiety, be careful. Read on to learn more about the claimed benefits and potential risks.

How does it work against depression and anxiety?

Kratom is not technically an opioid, but its effects are similar to those of opioids, such as morphine or codeine. The active ingredient in kratom is called mitragynine. Mitragynine binds to opioid receptors in the brain, which provides pain relief. This action could be the cause of the antidepressant and anxiolytic effects reported by some kratom users.There is currently very little research on the effects of kratom on mood. A 2017 review confirmed that in some users, kratom improves mood and relieves anxiety. The researchers also pointed out that kratom can have sedative effects. Researchers have yet to examine whether side effects such as sedation can interfere with its purported benefits.

Other alleged benefits

In addition to depression and anxiety, kratom is said to treat the following conditions:

  • pain
  • muscle aches
  • exhaustion
  • high blood pressure
  • opioid dependence and withdrawal
  • diarrhea
  • post-traumatic stress disorder (PTSD)

According to a 2017 review According to other studies, kratom also has anti-inflammatory, immune and appetite suppressant effects. More research is needed to confirm these benefits.

What exactly is kratom?

Kratom (Mitragyna speciosa ) is a tree found in parts of Southeast Asia, including Thailand and Malaysia. The active ingredient in Kratom, mitragynine, is found in its leaves. In low doses, mitragynine has energizing effects. At higher doses, it has sedative effects. In parts of Southeast Asia, people have used kratom for centuries. Other names for Kratom include:

  • biak
  • kakum / kakuam
  • ketum
  • thud
  • thom

Kratom is illegal in many countries around the world, including Australia, Thailand, and Denmark. Although it is legal in the United States, efforts have been made to restrict access to and regulate this substance.

How to use it and is it safe to ingest?

Kratom can be ingested in a variety of forms, including:

  • capsules
  • tablets
  • chewing gum
  • tinctures
  • excerpts

In some cases, kratom leaves are eaten fresh or dried, or boiled and consumed as tea. Dried leaves can also be ground into a powder and ingested. Kratom can be smoked or vaporized, but it’s less common. The method of ingestion can influence the effects of kratom. However, there is currently no research to determine which method is best for treating depression and anxiety.

Are there different types or strains?

Different types of kratom are called strains. Most strains of kratom get their name from their place of origin. As with strains of marijuana, different strains of kratom have slightly different effects. There is currently no research on the effects of different strains of kratom. The descriptions that follow are based solely on anecdotal reports. It should also be noted that the effects of a particular strain might vary from vendor to vendor.

Maeng Da

Green Maeng Da Kratom refers to several different types of allegedly strong and durable. Maeng da is originally from Thailand, but Indonesian and Malaysian strains of Maeng da are also available. Maeng da can be green, red or white in color. It is said to act as a stimulant, increasing energy while inducing feelings of well-being and reducing pain. Some people report feeling chatty after taking Maeng da.


Indo kratom comes from Indonesia. It can be green, red or white. Indo kratom is considered to be less stimulating than other strains, although some types may have mild energizing effects. In general, Indo strains are known to increase relaxation, relieve pain, and promote feelings of well-being. They are believed to help relieve anxiety.

Bali / red vein

Bali kratom originates from Indonesia. It is reddish in color and is believed to provide effective pain relief. Users say it is the most “opioid” of all kratom strains. It can help relieve pain-related conditions, such as depression or chronic pain.

Malaysian Green

Malayan green kratom comes from Malaysia. It is dark green in color. In low doses, it is said to provide energy and focus while relieving pain. In large doses, it may have a more sedating effect. It is said to help relieve anxiety.


Thai kratom comes from Thailand. Red, green, and white veined Thai kratom is available, and effects may vary by color. The strains of green and white veins are said to stimulate and create a euphoric “high”. Thai red vein kratom is said to relieve pain.


Borneo kratom comes from Borneo. It is available in red, green and white. Compared to other strains, Borneo kratom is considered to have a more sedating effect. It can be used to treat anxiety and stress.


Malaysian strains, including varieties of kratom with green, red and white veins, are believed to provide a balance between stimulating and sedating effects. Users report mood swings, pain relief, and increased energy and focus.

Are there dosage guidelines?

Little is known about kratom dosage guidelines for depression and anxiety. In general, the recommended dose depends on your age, gender and medical condition. Other factors, such as method of ingestion and strain, can also influence the effects of kratom. For example, kratom extract is considered to be much more potent than kratom powder. In a 2018 study based on a survey of 8,049 people who use kratom, most people reported that a dose of up to 5 grams of powder taken up to 3 times per day was sufficient to get effects.

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About the Author: Barry Lachey

Barry Lachey is a Professional Editor at Zobuz. Previously He has also worked for Moxly Sports and Network Resources "Joe Joe." he is a graduate of the Kings College at the University of Thames Valley London. You can reach Barry via email or by phone.